Acute intracranial hypertension after nalidixic acid administration.

Acute intracranial hypertension after nalidixic acid administration.

Nalidixic acid (Negram) is an antimicrobial agent widely used in the treatment of urinary tract infection. Some years ago Boreus and Sundstrom (1967) reported intracranial hypertension in a 6-month-old boy treated with nalidixic acid at the manufacturer's recommended dose. Only a few cases have been reported since, mostly in children treated either with large doses (Fisher, 1967) or for prolong...

Intracranial hypertension in a child during treatment with nalidixic acid.

Benign intracranial hypertension after ciprofloxacin administration.

Many drugs, including antibiotics, have been implicated in the aetiology of benign intracranial hypertension. We report the development of benign intracranial hypertension after the use of ciprofloxacin in a teenager with cystic fibrosis.

Benign intracranial hypertension after antibiotic therapy.

Benign intracranial hypertension or pseudotumour cerebri is a syndrome of increased intracranical pressure and bilateral papilloedema in a patient with normal or small ventricular systems in the absence of space-occupying lesions. No intracranial infection, hypertensive encephalopathy, or hypercapnic respiratory failure is found, and the cerebrospinal fluid content is normal. It has been descri...

Intracranial hypertension after traumatic brain injury

Introduction Traumatic brain injury (TBI) is a common and devastating problem with a high mortality and a high residual morbidity in survivors. The most cost effective measures of course are all preventative, including public health education, the mandatory use of seatbelts in cars and helmets on motorcycles, appropriate speed limits and improved road design. When an injury has occurred, howeve...